Bromination of phenacetin
WebThe literature melting point for phenacetin is 134-135 °C which is close to the experimental value found. The difference in the experimental melting point indicates the presence of slight impurities in the product. In lab 4, the phenacetin was … WebAdd 2.5 mL of glacial acetic acid and stir to dissolve phenacetin (potassium bromate will not dissolve at this point). Slowlyadd 0.225 mL of aqueous HBr (48% w/w) drop-wise and stir …
Bromination of phenacetin
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WebWestern Kentucky University WebBromination of Phenacetin Purpose: To perform an electrophilic aromatic substitution (EArS) reaction on disubstituted phenacetin by generating Br2 in situ ; to solve the substitution …
WebIn this experiment, you will attempt to brominate the phenacetin. Elemental bromine will not be used.Instead, bromine will be produced in the “pot” by reaction of hydrobromic acid with bromate ion (as shown below). This method is widely used for bromination of aromatics because it does not involve handling liquid bromine, which is quite corrosive. WebCHEM3412 Lab Electrophilic Bromination of Phenacetin H .. H . H .. KBrO3, HBr (aq) Br or ACOH Introduction Electrophilic aromatic substitution (EAS) can occur with many different electrophiles. In this experiment, you will attempt to brom... Show more... Show more Chemistry Science Organic chemistry Answer & Explanation
WebNov 1, 2011 · The bromination reactions of phenacetin, metoprolol, naproxen, and hydrochlorothiazide were conducted under pseudo-first-order conditions, in which the total bromine concentration was at least 10 times in excess with respect to the pharmaceutical concentration ( [Br] 0 ⩾ 5 mM vs. [Ph] 0 = 1 μM). Web1006 Bromination of 4-ethoxyacetanilide (phenacetin) to 3-bromo-4-ethoxyacetanilide Br HN O CH 3 O CH 3 HN O CH 3 O CH 3 KBrO 3, HBr acetic acid C 10H 13NO 2 C 10H …
Web4. Cleaning Up Place your recovered materials in the appropriate labeled collection con-tainers as directed by your laboratory instructor. Clean your glassware with soap or detergent. Caution: Wash your hands thoroughly with soap or detergent be-fore leaving the laboratory. Post-Laboratory Questions 1. Calculate the percent yield of phenacetin …
Web1. CHEM3412 Lab Synthesis of Benzocaine by Fischer Esterification. H 2 N. OH. O. EtOH H 2 N; OEt. O. H 2 O; H 2 SO 4 Benzocaine. Introduction Benzocaine is a local/topical anesthetic related to procaine (Novocain) and lidocaine. Benzocaine is the ethyl ester of para-aminobenzoic acid (PABA), a compound used in some sunscreens. consequences of meth addictionWebTransfer 200 mg of phenacetin and 63 mg of potassium bromate into a 25-mL Erlenmeyer flask equipped with magnetic stir bar. If you have less than 200 mg of pure … consequences of mishandling evidenceWebTransfer 200 mg of phenacetin and 63 mg of potassium bromate into a 25-mL Erlenmeyer flask equipped with magnetic stir bar. If you have less than 200 mg of pure … consequences of mislabeled specimensWebCHEM 110L Spring 2024 - Remote Lab Performed by Daniel Droege & Christin Cudahy Directed / Led by Jerah Barnett University of California, Santa Cruz editing metadata of imageWebDefine bromination. bromination synonyms, bromination pronunciation, bromination translation, English dictionary definition of bromination. tr.v. bro·mi·nat·ed , … consequences of mismanaging working capitalWebIntroductionElectrophilic aromatic substitution (EAS) can occur with many different electrophiles. In thisexperiment, you will attempt to brominate the phenacetin. … editing metadata for podcastsWebQuestion: Use the experimental procedure document for this experiment and calculate the theoretical yield and limiting reagent for the Bromination of trans-stilbene using the suggested masses of the reagents. The balanced chemical reaction is shown below. The products regardless of stereochemistry will have the same molar mass. Use the molar … editing metadata in photoshop