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WebMar 15, 2003 · Using ELL as the bait in a yeast 2-hybrid screen, we recently isolated a novel protein that we named EAF1 for E LL A ssociated F actor 1.14We found that … WebApr 1, 2024 · EAF1 and EAF2, the eleven-nineteen lysine-rich leukemia (ELL)-associated factors which can assemble to the super elongation complex (AFF1/4, AF9/ENL, ELL, and P-TEFb), are reported to participate in RNA polymerase II to actively regulate a variety of biological processes, including leukemia and embryogenesis, but whether and how … WebMay 1, 2024 · EAF1 and EAF2 are ELL-associated factors and considered as positive regulators of ELL. However, their role in HIV-1 transcriptional control is unknown. In this study, we show that EAF1/2 inhibit the SEC-dependent and Tat-activated HIV-1 transcription. EAF1/2 are found to interact with the SEC components in an ELL1/2 … imxrt1062 reference manual