Phloretin hydrolase
WebbPhlorizin is a glucoside of phloretin, a dihydrochalcone. A white solid, samples often appear yellow owing to impurities. It is of sweet taste and contains four molecules of water in the crystal. Above 200 °C, it decomposes to give rufin. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water. WebbInhibitor in Enzyme-catalyzed Reactions (18 results) compound shows little anti-Staphylococcus aureus activity, but significantly inhibit SrtB activity in vitro. Phloretin reduces human alveolar epithelial cell damage caused by Staphylococcus aureus. Phloretin directly localizes in the active pocket of SrtB and blocks substrate binding.
Phloretin hydrolase
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Webb2,4-DAPG; Friedel–Crafts hydrolase; MAPG; PhlG; phloretin hydrolase Correspondence Y.-X. He, MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou 730000, China Tel: +86 0932 8912563 E-mail: [email protected] Jian-Ting Han and Si-Ping Zhang contributed equally to this work Webbphloretin hydrolase Alternative Name(s) C-acylphenol hydrolase: Reaction catalysed; H2O + phloretin => 1,3,5-trihydroxybenzene + H(+) + phloretate: Comment(s) Also hydrolyzes other C-acylated phenols related to phloretin. Isolated from the fungus Aspergillus niger and the bacteria Pantoea agglomerans and Eubacterium ramulus.
WebbThe enzyme phloretin hydrolase was purified from cells of E. herbicola Y46 grown on Yeast Beef Broth, by treatment of crude extracts with protamine sulfate, ammonium … WebbPhloretin hydrolase SpringerLink Enzyme Handbook 4 pp 1131–1134 Cite as Phloretin hydrolase Dietmar Schomburg & Margit Salzmann Chapter 16 Accesses Keywords …
Webb1 okt. 2004 · Phloretin hydrolase was assayed in 50 mM potassium phosphate buffer (pH 7.0) containing 60 μM phloretin (Roth, Karlsruhe, Germany) added from a 1.2 mM stock solution in dimethyl sulfoxide (DMSO). DMSO (final concentration, 5% [vol/vol]) reduced the phloretin hydrolase activity by approximately 15%. In an animal model, phloretin inhibited active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin. An important effect of this is the inhibition of glucose absorption by the small intestine and the inhibition of renal glucose reabsorption. Phloretin also … Visa mer Phloretin is a dihydrochalcone, a type of natural phenol. It can be found in apple tree leaves and the Manchurian apricot. Visa mer In rats, ingested phlorizin is converted into phloretin by hydrolytic enzymes in the small intestine. Phloretin hydrolase hydrolyses phloretin into phloretic acid and phloroglucinol Visa mer • Phlorizin is the 2'-glucoside of phloretin • Naringin dihydrochalcone is a diglycoside of phloretin Visa mer Phloretin functionalized gold-nanoparticles (Pht-GNPs) were synthesized using a single-step synthesis method and tested for its anticancer activity. Pht-GNPs … Visa mer • Phloretin-glucosidase Visa mer
WebbIn enzymology, a phloretin hydrolase (EC 3.7.1.4) is an enzyme that catalyzes the chemical reaction. phloretin + H 2 O phloretate + phloroglucinol. Thus, the two substrates of this enzyme are phloretin and H 2 O, whereas its two products are …
Webb19 feb. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the … tree financingWebb14 nov. 2013 · Phloretin hydrolase from Eubacterium ramulus (Phy) catalyzes the hydrolysis of the dihydrochalcone phloretin to phloroglucinol and phloretic acid, performi … treefindpathWebbAbstract. A metagenome expression library of bulk DNA extracted from the rumen content of a dairy cow was established in a phage lambda vector and activity-based screening employed to explore the functional diversity of the microbial flora. Twenty-two clones specifying distinct hydrolytic activities (12 esterases, nine endo-beta-1,4-glucanases ... tree filter stormwaterWebb1 apr. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for most members of this family is still unknown ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure tree finesse limitedWebbFEBS Press tree finder by pictureWebb19 feb. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for … treefinity jewelleryWebbLactase-phlorizin hydrolase may refer to: Phloretin hydrolase, an enzyme Glycosylceramidase, an enzyme This set index page lists enzyme articles associated … tree fingerplays